Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Brain Cancer treatment details. Biologic therapy. Chemotherapy. Clinical Center of the National Institutes of Health, Bethesda,MD, United States



Survival: 7.1 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Bethesda,MD
   
Hospital: Clinical Center of the National Institutes of Health
   
Journal: Link
   
Date: 2/2009

Description:
Patients:
This phase II trial involved 48 recurrent glioblastoma patients, 28 (58%) of whom were male. The median age of the group was 53 years, with a range of 21-69.

Treatment:
Patients were administered the biologic therapy bevacizumab, followed by the chemotherapy drug irinotecan.

Toxicities:
The highest toxicity grade reported was grade 4, which was for thromboembolic events including pulmonary embolism. Grade 3 hypertension (2 patients), liver problems (1 patient), and bowel perforation (1 patient) was also reported.

Results:
Median overall survival in this study was 7.1 months.

Correspondence: Dr. Howard A. Fine; email: hfine@mail.nih.gov

E-mail to a Friend Email Physician More Information