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Lung Cancer treatment details. Chemotherapy. Radiation. Yokohama Municipal Citizen's Hospital, Yokohama, Japan



Survival: 16.4 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
Radiation
   
Drugs:
Country: Japan
   
City/State/Province: Yokohama
   
Hospital: Yokohama Municipal Citizen's Hospital
   
Journal: Link
   
Date: 12/2009

Description:
Patients:
This phase II study involved 26 patients with unresectable stage III non-small cell lung cancer. Of these, 84.6% were male and the median age was 63 years.

Treatment:
Patients were treated with a combination of the chemotherapy drugs cisplatin (also called CDDP) and irinotecan (also called CPT-11), followed by thoracic radiotherapy and chemotherapy with carboplatin (also called CBDCA).

Toxicities:
One patient died due to treatment-related toxicity during this study. Grade 3 or 4 neutropenia (53.8% of patients) and diarrhea (19.2%) was also reported.

Results:
Median overall survival in this study was 16.4 months.

Correspondence: Dr. Hiroaki Okamoto; email: scyooka@alles.or.jp

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