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Lung Cancer treatment details. Chemotherapy. Radiation. Stanford University, Stanford, CA, United States



Survival: 21.0 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
Radiation
   
Drugs:
Country: United States
   
City/State/Province: Stanford, CA
   
Hospital: Stanford University
   
Journal: Link
   
Date: 6/2009

Description:
Patients:
This study involved 68 patients with limited-stage small-cell lung cancer. The median age was 63, with a range of 39-86, and 44% were male.

Treatment:
Patients were given a combination of the chemotherapy agents tirapazamine, cisplatin, and etoposide, which cause DNA damage and cancer cell death. In addition, patients received thoracic radiotherapy.

Toxicities:
Two deaths were reported as a result of these treatments. One was due to disease progression and the other to pericardial effusion. The most common grade 3 and 4 toxicities were leucopenia, neutropenia, and dehydration.

Results:
The estimated median overall survival for this study was 21 months.

Correspondence: Le QT; email: Qle@stanford.edu

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