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Brain Cancer treatment details. Chemotherapy. Radiation. University of Wisconsin Medical School, Madison, Wisconsin, United States



Survival: 10.9 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
Radiation
   
Drugs:
Country: United States
   
City/State/Province: Madison, Wisconsin
   
Hospital: University of Wisconsin Medical School
   
Journal: Link
   
Date: 7/2004

Description:
Patients: This Phase I study involved 26 patients with glioblastoma multiforme and 5 patients with anaplastic astrocytoma.

Treatment: Treatment consisted of iododeoxyuridine (a potential radio-sensitizing agent) combined with hyperfractionated accelerated radiotherapy.

Toxicity: Grade 4 toxicities included neutropenia, diarrhea, and prothrombin time increase. Grade 3 toxicities included thrombocytopenia, enzyme elevation, skin, and neuromotor deficits.

Results: The overall survival for the glioblastoma patients was 10.9 months.

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