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Ovarian Cancer treatment details. Chemotherapy. Copenhagen University Hospital, Copenhagen, Denmark

Survival: 12.5 months
Toxicity Grade: 5
Treatments: Chemotherapy
Country: Denmark
City/State/Province: Copenhagen
Hospital: Copenhagen University Hospital
Journal: Link
Date: 10/2010

This study involved 79 women with recurrent epithelial ovarian cancer with a median age of 59 years (range 31-77).

Patients were treated with two chemotherapy agents, gemcitabine and pegylated liposomal doxorubicin (PLD), which stop cancer cell growth by inhibiting cell division.

There was one treatment-related death reported in this study, which was attributed to lung inflammation. Other grade 3 or 4 toxicities reported were febrile neutropenia, hand-foot skin reactions, mucositis (mouth sores), and nausea.

The median overall survival in this study was 12.5 months and median progression-free survival was 6.4 months.

This study was partially supported by Eli Lilly, makers of gemcitabine (brand name Gemzar), and Schering Plough.

Correspondence: Dr. Mansoor R. Mirza; email:

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