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Melanoma treatment details. Chemotherapy. University of California Davis Cancer Center, Sacramento, CA, United States



Survival: 7.3 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Sacramento, CA
   
Hospital: University of California Davis Cancer Center
   
Journal: Link
   
Date: 10/2010

Description:
Patients:
This study involved 17 metastatic melanoma patients with a median age of 53 years (range 34-85) and 35% male.

Treatment:
Patients in this study received a chemotherapy agent called UCN-01 (or 7-hydroxystaurosporine), which blocks cell growth of cancer cells.

Toxicities:
The maximum toxicity level reported in this study was grade 4, which included one case each of anemia and elevated creatinine level. The most common toxicities were hyperglycemia (65% of patients), nausea (53%), and anemia (grade 1-4; 41%)

Results:
The median progression free survival was 1.3 months. Median overall survival was 7.3 months.

Correspondence: Dr. Tianhong Li; email: tianhong.li@ucdmc.ucdavis.edu

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