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Melanoma treatment details. Chemotherapy. University of California Davis Cancer Center, Sacramento, CA, United States

Survival: 7.3 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: United States
City/State/Province: Sacramento, CA
Hospital: University of California Davis Cancer Center
Journal: Link
Date: 10/2010

This study involved 17 metastatic melanoma patients with a median age of 53 years (range 34-85) and 35% male.

Patients in this study received a chemotherapy agent called UCN-01 (or 7-hydroxystaurosporine), which blocks cell growth of cancer cells.

The maximum toxicity level reported in this study was grade 4, which included one case each of anemia and elevated creatinine level. The most common toxicities were hyperglycemia (65% of patients), nausea (53%), and anemia (grade 1-4; 41%)

The median progression free survival was 1.3 months. Median overall survival was 7.3 months.

Correspondence: Dr. Tianhong Li; email:

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