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Prostate Cancer treatment details. Chemotherapy. Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, United States

Survival: 19.4 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: United States
City/State/Province: Cleveland, OH
Hospital: Cleveland Clinic Taussig Cancer Institute
Journal: Link
Date: 10/2010

This phase 2 trial involved 35 male metastatic castration-resistant prostate cancer patients with a median age of 67 years and a range of 55-84.

Patients in this study were administered a combination of two chemotherapy agents, gemcitabine and docetaxel.

The maximum toxicity level reported was grade 4. The most common grade 3 and 4 toxicity was neutropenia (48% of patients). Grade 3 fatigue was experienced by 15% of patients. Grade 1 and 2 alopecia or fatigue was reported for 80% and 69% of patients, respectively.

The median overall survival reported for this study was 19.4 months.

This study was supported by Bayer Pharmaceuticals and Onyx Pharmaceuticals.

Correspondence: Dr. Jorge A. Garcia; email:

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