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Melanoma treatment details. Biologic therapy. The University of Texas M.D. Anderson Cancer Center, Houston, TX, United States



Survival: 7.5 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Houston, TX
   
Hospital: The University of Texas M.D. Anderson Cancer Center
   
Journal: Link
   
Date: 9/2008

Description:
Patients:
This phase 2 study involved 21 patients with metastatic melanoma. The median age of the patient group was 58 (range of 33-83) years and 62% were male.

Treatment:
Patients were treated with a biologic therapy agent called imatinib mesylate, which inhibits protein tyrosine kinases that are involved in the growth of cancer cells.

Toxicities:
The most severe toxicities reported were one case each of grade 4 fatigue and edema (fluid retention). Other toxicities included grade 1 and 2 nausea and anorexia.

Results:
The median overall survival was reported as 7.5 months.

Correspondence: Dr. Omar Eton; email: omar.eton@mpi.com

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