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Melanoma treatment details. Biologic therapy. The University of Texas M.D. Anderson Cancer Center, Houston, TX, United States

Survival: 7.5 months
Toxicity Grade: 4
Treatments: Biologic therapy
Country: United States
City/State/Province: Houston, TX
Hospital: The University of Texas M.D. Anderson Cancer Center
Journal: Link
Date: 9/2008

This phase 2 study involved 21 patients with metastatic melanoma. The median age of the patient group was 58 (range of 33-83) years and 62% were male.

Patients were treated with a biologic therapy agent called imatinib mesylate, which inhibits protein tyrosine kinases that are involved in the growth of cancer cells.

The most severe toxicities reported were one case each of grade 4 fatigue and edema (fluid retention). Other toxicities included grade 1 and 2 nausea and anorexia.

The median overall survival was reported as 7.5 months.

Correspondence: Dr. Omar Eton; email:

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