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Mesothelioma Cancer treatment details. Chemotherapy. Kinki University School of Medicine, Ohnohigashi, Osakasayama, Japan



Survival: 7.3 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
   
Drugs: Pemetrexed
Country: Japan
   
City/State/Province: Ohnohigashi, Osakasayama
   
Hospital: Kinki University School of Medicine
   
Journal: Link
   
Date: 5/2008

Description:
Patients:
This study involved 25 patients with malignant pleural mesothelioma who had not received prior chemotherapy. Of these, 22 were male, and the median age was 61 years.

Treatment:
Patients in this study were given a combination of cisplatin and pemetrexed, which are chemotherapy agents.

Toxicity:
There was one treatment-related death due to worsening of pre-existing pneumonia in this study. Other reported adverse events due to treatment included leukopenia, nausea, and anorexia.

Results:
The reported median overall survival was 7.3 months.

Support:
This study was funded by Eli Lilly, the makers of pemetrexed (brand name Alimta).

Correspondence: Dr. Kazuhiko Nakagawa; email: nakagawa@med.kindai.ac.jp

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