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Brain Cancer treatment details. Chemotherapy. UTMD Anderson Cancer Center, Houston, Texas, United States



Survival: ?
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Temodar
Country: United States
   
City/State/Province: Houston, Texas
   
Hospital: UTMD Anderson Cancer Center
   
Journal: Link
   
Date: 9/2000

Description:
Patients: This Phase II study involved 225 glioblastoma multiforme patients at first relapse who were divided into two groups of 112 patients and 113 patients.

Treatment: The group of 112 patients were administered the chemotherapy drug temozolomide. The group of 113 patients were administered the chemotherapy drug procarbazine.

Toxicity: For both groups, grade 3-4 toxicities included: nausea, vomiting, fatigue, constipation, headache, thrombocytopenia, neutropenia, and anemia.

Results: For the temozolomide group of patients, the 6-month progression free survival rate was 21%. Overall median survival was not detailed.

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