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Brain Cancer treatment details. Chemotherapy. Istituto Nazionale Neurologico 'Carlo Besta', Milan, Italy



Survival: ?
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Platinol
Temodar
Country: Italy
   
City/State/Province: Milan
   
Hospital: Istituto Nazionale Neurologico 'Carlo Besta'
   
Journal: Link
   
Date: 1/2004

Description:
Patients: This Phase II study involved 20 patients with inoperable glioblastoma multiforme and 13 patients with inoperable anaplastic astrocytoma.

Treatment: Treatment consisted of two chemotherapy drugs, cisplatin and temozolomide.

Toxicity: There were grade 3-4 hematological toxicities. Other toxicities included ototoxicity, neurotoxicity, renal, hepatic, and nausea/vomiting.

Results: At 12 months 86.2% of glioblastoma patients had their tumors progress (grow).

Correspondence: Antonio Silvani, MD

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