Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Prostate Cancer treatment details. Chemotherapy. Memorial Sloan-Kettering Cancer Center, New York, NY, United States



Survival: 17.8 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: New York, NY
   
Hospital: Memorial Sloan-Kettering Cancer Center
   
Journal: Link
   
Date: 6/2011

Description:
Patients:
This phase III study involved men with castration-resistant prostate cancer. Patients were divided into two treatment groups. Group A consisted of 476 patients with a median age of 70.9 years. Group B had 477 patients with a median age of 70.4 years.

Treatment:
Group A was treated with the chemotherapy agent docetaxel and the steroid prednisone. Group B received docetaxel and the chemotherapy agent calcitriol.

Toxicities:
Deaths not due to disease progression were reported for both groups (adverse event grade 5) but specific causes were not given. Grade 3 or higher deep vein thrombosis, anemia, fatigue, and neutropenia were reported.

Results:
The median overall survival was 20.2 months for group A and 17.8 months for group B.

Support:
This study was supported by Novacea, makers of DN-101 (calcitriol).

Correspondence: Dr. Howard I. Scher; email: scherh@mskcc.org

E-mail to a Friend Email Physician More Information