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Lung Cancer treatment details. Biologic therapy. Kyoto University Hospital, Kyoto, Japan



Survival: 7.5 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: Japan
   
City/State/Province: Kyoto
   
Hospital: Kyoto University Hospital
   
Journal: Link
   
Date: 4/2011

Description:
Patients:
This study involved 48 patients with previously treated advanced non-small cell lung cancer. The median age of the group was 62 years and 52% were male.

Treatment:
Patients were treated with the biologic therapy called erlotinib, which is a small molecular inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase, which is involved in cell growth and survival.

Toxicities:
There was one treatment-related death due to pneumonia. Also, grade 3-4 anorexia, fatigue, and stomatitis (inflammation of the mouth) was reported.

Results:
The reported median overall survival was 7.5 months.

Support:
Researchers received funding from pharmaceutical companies Taiho Pharmaceuticals and Chugai Pharmaceuticals.

Correspondence: Dr. Kazuhiro Yanagihara; email: kazuhiro@kuhp.kyoto-u.ac.jp

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