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Prostate Cancer treatment details. Biologic therapy. Chemotherapy. Hormone. National Cancer Institute, Bethesda, MD, United States



Survival: 28.2 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
Hormone
   
Drugs:
Country: United States
   
City/State/Province: Bethesda, MD
   
Hospital: National Cancer Institute
   
Journal: Link
   
Date: 4/2010

Description:
Patients:
This study involved 60 male patients with metastatic castration-resistant prostate cancer. The median age of the group was 66 years with a range of 44-79.

Treatment:
Patients were treated with a combination of the chemotherapy agent docetaxel, the biologic therapy agents thalidomide and bevacizumab, and the hormone prednisone.

Toxicities:
One death due to heart attack was reported. In addition, all patients reported grade 3-4 neutropenia and 33 reported grade 2 constipation.

Results:
The reported median overall survival was 28.2 months.

Correspondence: Dr. William D. Figg; email: wdfigg@helix.nih.gov

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