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Brain Cancer treatment details. Chemotherapy. Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland



Survival: 7.6 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: Switzerland
   
City/State/Province: Lausanne
   
Hospital: Centre Hospitalier Universitaire Vaudois
   
Journal: Link
   
Date: 2/2011

Description:
Patients:
This study involved 37 glioblastoma patients who had previously been treated and had recurrence or progression of their disease. The median patient age was 57 years and 76% were male.

Treatment:
Patients were treated with a chemotherapy agent called sagopilone, also known as ZK-EPO or ZK-219477.

Toxicity
The maximum toxicity level reported was of grade 4, consisting of one case of peripheral neuropathy. Also reported were 3 cases each of grade 3 fatigue and neutropenia.

Results:
The reported median overall survival was 7.6 months.

Support:
This study was supported by Bayer Schering Pharma, makers of sagopilone.

Correspondence: Dr. Roger Stupp; email: roger.stupp@chuv.ch

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