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Colon Cancer treatment details. Chemotherapy. Nihon University School of Medicine, Tokyo, Japan

Survival: 27.6 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Leucovorin
Country: Japan
City/State/Province: Tokyo
Hospital: Nihon University School of Medicine
Journal: Link
Date: 3/2011

This phase II study involved 58 patients with metastatic colorectal cancer, 36 of whom were male. The median patient age was 67.5 years.

Patients were treated with the chemotherapy combination termed FOLFOX4, which includes the agents 5-fluorouracil, oxaliplatin, and leucovorin.

The most severe adverse events were of grade 4, including 10 cases of neutropenia. Also, grade 1-3 peripheral neuropathy (tingling or numbness) was reported.

The reported median progression-free survival and overall survival were 10.2 and 27.6 months, respectively.

Correspondence: Dr. Wataru Ichikawa; email:

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