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Ovarian Cancer treatment details. Biologic therapy. Indiana University School of Medicine, Indianapolis, IN, United States

Survival: 16.3 months
Toxicity Grade: 5
Treatments: Biologic therapy
Country: United States
City/State/Province: Indianapolis, IN
Hospital: Indiana University School of Medicine
Journal: Link
Date: 1/2011

This study involved 71 women with recurring ovarian cancer or primary peritoneal carcinomatosis. The median patient age was 60 years.

Patients were treated with the biologic therapy agent sorafenib, which is a protein kinase inhibitor that is involved in the growth of cancer cells.

There was one treatment-related death due to sepsis reported for this study. Also reported were dermatologic (grades 1-3), gastrointestinal (1-3), constitutional (fever and/or general aches, grades 1-4), and metabolic (1-4) effects.

The median progression-free survival and overall survival were 2.1 and 16.33 months, respectively.

Correspondence: Dr. Daniela Matei; email:

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