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Lung Cancer treatment details. Biologic therapy. VU University Medical Center Amsterdam, Amsterdam, Netherlands



Survival: 10.9 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: Netherlands
   
City/State/Province: Amsterdam
   
Hospital: VU University Medical Center Amsterdam
   
Journal: Link
   
Date: 6/2010

Description:
Patients:
This study involved 50 patients with advanced non-small cell lung cancer who had not received previous chemotherapy. The median patient age was 60 years and 56% were male.

Treatment:
Patients were treated with the biologic therapy agents erlotinib and sorafenib.

Toxicities:
There was 1 reported treatment-related death due to pulmonary hemorrhage. Grade 3 fatigue (16% of patients), hand-foot syndrome (16%), and diarrhea (14%) were also reported.

Results:
The median overall survival was 10.9 months.

Support:
This study was supported by Bayer Pharmaceuticals, makers of sorafenib.

Correspondence: Dr. Egbert F. Smit; email: ef.smit@vumc.nl

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