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Colon Cancer treatment details. Biologic therapy. University of Chicago, Chicago, IL, United States

Survival: 5.1 months
Toxicity Grade: 5
Treatments: Biologic therapy
Country: United States
City/State/Province: Chicago, IL
Hospital: University of Chicago
Journal: Link
Date: 5/2011

This phase II study involved 19 patients with previously treated metastatic colorectal cancer. The median patient age was 64 years and 58% were male.

Patients were treated with the biologic therapy agent called dasatinib, which is an inhibitor of protein-tyrosine kinases, and therefore interferes with internal signals in cancer cells.

Treatment-related death due to heart attack was reported for this study. Grade 3 fatigue, anemia, anorexia, and nausea/vomiting were also reported.

The reported median overall survival was 5.1 months.

Correspondence: Dr. Hedy L. Kindler; email:

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