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Liver Cancer treatment details. Chemotherapy. National Cancer Center Hospital East, Kashiwa, Japan



Survival: 16.6 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: Japan
   
City/State/Province: Kashiwa
   
Hospital: National Cancer Center Hospital East
   
Journal: Link
   
Date: 12/2010

Description:
Patients:
This phase II study involved 23 patients with advanced hepatocellular carcinoma (HCC) who had a median age of 68 years and 91.3% were male.

Treatment:
Patients were treated with the chemotherapy agent called S-1.

Toxicities:
The highest toxicity grade reported was grade 4. Grade 3/4 toxicities included decreased hemoglobin, lymphopenia, thrombocytopenia, and fatigue.

Results:
The median overall survival was 16.6 months and the median progression-free survival was 3.7 months.

Support:
This study was supported by Taiho Pharmaceutical Co., Ltd., makers of S-1.

Correspondence: Dr. Junji Furuse; email: jfuruse@ks.kyorin-u.ac.jp

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