Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results

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Brain Cancer treatment details. Chemotherapy. National Cancer Institute, Bethesda, MD, United States

Survival: 7.8 months
Toxicity Grade: 4
Treatments: Chemotherapy
Country: United States
City/State/Province: Bethesda, MD
Hospital: National Cancer Institute
Journal: Link
Date: 5/2011

This phase II study involved 40 patients with recurrent glioblastoma who had received prior treatment. The median patient age was 55 years and 75% were male.

Patients were treated with the chemotherapy agent romidepsin, which interferes with cancer cell DNA replication.

The most severe reported adverse events were of grade 4 and included fatigue and thrombosis. Also reported were grade 3 neutropenia, lymphopenia, and thrombocytopenia.

The reported median overall survival was 7.8 months.

Correspondence: Dr. Howard Fine; email:

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