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Brain Cancer treatment details. Chemotherapy. Emory University School of Medicine, Atlanta, Georgia, United States

Survival: 7.4 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Camptosar
Country: United States
City/State/Province: Atlanta, Georgia
Hospital: Emory University School of Medicine
Journal: Link
Date: 8/2003

Patients: This Phase I study involved 40 patients with recurrent malignant gliomas. Thirty-four patients had glioblastoma multiforme, five had anaplastic astrocytoma, and one patient had an anaplastic oligodendroglioma.

Treatment: The treatment consisted of administration of the chemotherapy drug, irinotecan (camptosar).

Toxicity: Dose limiting toxicities included grade 3 abdominal cramping, grade 4 diarrhea, and febrile neutropenia.

Results: Median overall survival was 7.4 months for all patients.

Correspondence: Joy D. Fisher, MD

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