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Ovarian Cancer treatment details. Biologic therapy. University of Colorado Denver, Aurora, CO, United States



Survival: 11.6 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Aurora, CO
   
Hospital: University of Colorado Denver
   
Journal: Link
   
Date: 10/2011

Description:
Patients:
This phase II study involved 54 women with previously treated epithelial ovarian cancer or primary peritoneal cancer. The median patient age was 62 years.

Treatment:
Patients were treated with the biologic therapy agent temsirolimus, which is an inhibitor of a protein involved in cancer cell growth called mTOR.

Toxicities:
The most severe adverse events were grade 4 fatigue and pulmonary embolism. Grade 3 mucositis (inflammation of the GI tract) and dehydration were also reported.

Results:
The median overall survival was 11.6 months.

Correspondence: Dr. Kian Behbakht; email: kian.behbakht@ucdenver.edu

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