Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Brain Cancer treatment details. Biologic therapy. Chemotherapy. Mayo Clinic, Rochester, MN, United States



Survival: 3.2 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Rochester, MN
   
Hospital: Mayo Clinic
   
Journal: Link
   
Date: 11/2011

Description:
Patients:
This phase II study involved 37 recurrent glioblastoma (GBM) patients with a median age of 51.5 years; 73% were male.

Treatment:
Patients were treated with the chemotherapy drug vorinostat and the biologic therapy drug bortezomib, which inhibits the proteasome complex in cells and causes cell death.

Toxicities:
The most severe adverse reactions were grade 4 thrombocytopenia and neutropenia. Grade 3 fatigue was also reported.

Results:
The median overall survival was 3.2 months.

Correspondence: Dr. Evanthia Galanis; email: galanis.evanthia@mayo.edu

E-mail to a Friend Email Physician More Information