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Bladder Cancer treatment details. Chemotherapy. Sapporo Medical University Urologic Oncology Consortium, Sapporo, Japan



Survival: 8.9 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: Japan
   
City/State/Province: Sapporo
   
Hospital: Sapporo Medical University Urologic Oncology Consortium
   
Journal: Link
   
Date: 6/2011

Description:
Patients:
This phase II study involved 45 previously-treated metastatic urothelial carcinoma patients with a median age of 68 years; 32 patients were male.

Treatment:
Patients in this study were treated with the chemotherapy agents paclitaxel, ifosfamide, and nedaplatin.

Toxicities:
The most severe adverse reactions were of grade 4 and included leukopenia (46.7% of patients), neutropenia (91.1%), and thrombocytopenia (6.7%). Also, all patients reported grade 2 alopecia.

Results:
The median overall survival was 8.9 months.

Correspondence: Dr. Hiroshi Kitamura; email:hkitamu@sapmed.ac.jp

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