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Bladder Cancer treatment details. Chemotherapy. University Hospital Del Mar, Barcelona, Spain



Survival: 6.9 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
   
Drugs:
Country: Spain
   
City/State/Province: Barcelona
   
Hospital: University Hospital Del Mar
   
Journal: Link
   
Date: 9/2009

Description:
Patients:
This phase III study involved 253 patients with a type of bladder cancer called transitional cell carcinoma of the urothelial tract. Patients had received prior platinum-containing chemotherapy. The median patient age was not given, but 46.6% of the patients were at least 65 years old.

Treatment:
Patients in this study were treated with the chemotherapy agent vinflunine.

Toxicities:
There was one treatment-related death due to pancytopenia (decrease in both red and white blood cells). Grade 3-4 neutropenia, fatigue, anemia, and constipation were also reported.

Results:
The reported median overall survival was 6.9 months.

Support:
This study was supported by the pharmaceutical company Pierre Fabre, makers of vinflunine.

Correspondence: Dr. Joaquim Bellmunt; email: jbellmunt@imas.imim.es

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