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Bladder Cancer treatment details. Biologic therapy. University Hospital Del Mar, Barcelona, Spain



Survival: 8.1 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: Spain
   
City/State/Province: Barcelona
   
Hospital: University Hospital Del Mar
   
Journal: Link
   
Date: 12/2011

Description:
Patients:
This phase II study involved 38 patients with untreated urothelial cancer. The median patient age was 75 years and 79% were male.

Treatment:
Patients were treated with the biologic therapy agent sunitinib, which is a tyrosine kinase inhibitor that causes an inhibition of tumor growth.

Toxicity:
There were 2 treatment-related deaths due to heart failure and stroke. Grade 4 thrombocytopenia and grade 3 fatigue were also reported.

Results:
The median overall survival was 8.1 months.

Support:
This study was partially supported by Pfizer, the makers of sunitinib.

Correspondence: Dr. J. Bellmunt; email: jbellmunt@parcdesalutmar.cat

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