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Non-Hodgkin's Lymphoma treatment details. Chemotherapy. Hormone. University of Southern California, Los Angeles, California, United States



Survival: 14.5 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
Hormone
   
Drugs:
Country: United States
   
City/State/Province: Los Angeles, California
   
Hospital: University of Southern California
   
Journal: Link
   
Date: 2/2007

Description:
Patients:
This study involved 19 non-Hodgkin’s lymphoma patients with a median age of 50 years; 47% were male.

Treatment:
Patients were treated with the chemotherapy agents pixantrone, cisplatin, and cytosine arabinoside, as well as the steroid hormone methylprednisolone.

Toxicity:
The most severe toxicities were of grade 4 and included anemia, neutropenia, and thrombocytopenia. Grade 3 fatigue, anorexia, and deep vein thrombosis were also reported.

Results:
The median overall survival was 14.5 months.

Support:
One of the authors of this study was employed by Cell Therapeutics, Inc., makers of pixantrone.

Correspondence: Dr. Alexandra M. Levine; email: alevine@usc.edu

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