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Brain Cancer treatment details. Immunotherapy. China Medical University and Hospital, Taichung, Taiwan Region



Survival: 17.1 months
   
Toxicity Grade: 4
   
Treatments: Immunotherapy
   
Drugs:
Country: Taiwan Region
   
City/State/Province: Taichung
   
Hospital: China Medical University and Hospital
   
Journal: Link
   
Date: 8/2011

Description:
Patients:
This study involved 17 malignant glioma patients with an average age of 44.7 years; 8 were male.

Treatment:
Patients were treated with an autologous dendritic cell tumor vaccine, which is an immunotherapy agent. For this treatment, immune cells (dendritic cells) are removed from a patientís blood sample, treated in a laboratory, and then injected back into the patient in order to cause an anti-tumor immune response.

Toxicities:
Grade 4 lymphopenia was the most severe reported adverse event. Liver toxicity was also reported.

Results:
The median overall survival was 17.1 months.

Correspondence: Dr. Wen-Kuang Yang; email: wkyang@mail.cmu.edu.tw

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