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Mesothelioma Cancer treatment details. Biologic therapy. UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, United States



Survival: 10.0 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: San Francisco, CA
   
Hospital: UCSF Helen Diller Family Comprehensive Cancer Center
   
Journal: Link
   
Date: 12/2011

Description:
Patients:
This phase II study involved 47 untreated malignant mesothelioma patients with a median age of 75 years; 91% were male.

Treatment:
Patients were treated with the biologic therapy agent vatalinib, which inhibits proteins involved in supporting tumor blood supply.

Toxicities:
The most severe toxicities were of grade 4 and included nausea, liver toxicity, and granulocytopenia.

Results:
The median overall survival was 10.0 months.

Correspondence: Dr. Thierry Jahan; email: tjahan@medicine.ucsf.edu

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