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Mesothelioma Cancer treatment details. Biologic therapy. UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, United States

Survival: 10.0 months
Toxicity Grade: 4
Treatments: Biologic therapy
Country: United States
City/State/Province: San Francisco, CA
Hospital: UCSF Helen Diller Family Comprehensive Cancer Center
Journal: Link
Date: 12/2011

This phase II study involved 47 untreated malignant mesothelioma patients with a median age of 75 years; 91% were male.

Patients were treated with the biologic therapy agent vatalinib, which inhibits proteins involved in supporting tumor blood supply.

The most severe toxicities were of grade 4 and included nausea, liver toxicity, and granulocytopenia.

The median overall survival was 10.0 months.

Correspondence: Dr. Thierry Jahan; email:

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