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Colon Cancer treatment details. Chemotherapy. Various, Athens, Greece



Survival: 15.0 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
   
Drugs: Adrucil
Camptosar
Leucovorin
Country: Greece
   
City/State/Province: Athens
   
Hospital: Various
   
Journal: Link
   
Date: 1/2003

Description:
Patients: This Phase II study involved 55 patients with advanced colorectal carcinoma.

Treatment: Treatment consisted of three chemotherapy drugs irinotecan (camptosar, CPT-11), leucovorin, and 5-fluorouracil (5-FU, adrucil)

Toxicity: There was one toxic death because of diarrhea, neutropenia, bacteremia, and sepsis. Other toxicities included: leucopenia (grade 1-3), neutropenia (grade 1-3), anemia (grade 1-2), thrombocytopenia (grade 3), nausea/vomiting (grade1-2), asthenia (grade 1-3).

Results: The median overall survival was 15.0 months

Correspondence: H.P. Kalofonos

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