Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Melanoma treatment details. Biologic therapy. Chemotherapy. Cambridge Biomedical Research Centre, Cambridge, United Kingdom



Survival: 8.5 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United Kingdom
   
City/State/Province: Cambridge
   
Hospital: Cambridge Biomedical Research Centre
   
Journal: Link
   
Date: 7/2011

Description:
Patients:
This phase II study involved 83 advanced melanoma patients who were not previously treated with chemotherapy. The median patient age was 56 years and 60% were male.

Treatment:
Patients were treated with the chemotherapy agent dacarbazine and the biologic therapy agent sorafenib, which is an angiogenesis inhibitor that inhibits blood supply to the tumor.

Toxicities:
There was one reported treatment-related death due to brain hemorrhage. Grade 3-4 neutropenia, low platelet count, and fatigue were also reported.

Results:
The median overall survival was 8.5 months.

Support:
Some of the authors were employed by Bayer Pharmaceuticals.

Correspondence: Dr. T Eisen; email: tgqe2@cam.ac.uk

E-mail to a Friend Email Physician More Information