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Liver Cancer treatment details. Biologic therapy. Queen Mary Hospital, Hong Kong, China

Survival: 4.3 months
Toxicity Grade: 3
Treatments: Biologic therapy
Country: China
City/State/Province: Hong Kong
Hospital: Queen Mary Hospital
Journal: Link
Date: 3/2012

This phase II study involved 10 advanced hepatocellular carcinoma patients who had been previously treated with the biologic therapy agent sorafenib. The median patient age was 47 years and 70% were male.

Patients were treated with a combination of two biologic therapy agents, bevacizumab and erlotinib (a small molecular inhibitor of epidermal growth factor receptor tyrosine kinase, which is involved in cell growth and survival).

The most severe treatment-related toxicities were of grade 3 and included rash, diarrhea, and vomiting.

The median overall survival was 4.37 months.

Correspondence: Dr. Thomas Yau; email:

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