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Colon Cancer treatment details. Chemotherapy. H˘pital Saint-Antoine, Paris, France



Survival: 13.9 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Pemetrexed
Country: France
   
City/State/Province: Paris
   
Hospital: H˘pital Saint-Antoine
   
Journal: Link
   
Date: 4/2010

Description:
Patients:
This study involved 44 patients with metastatic colorectal cancer who had received previous chemotherapy with 5-FU, leucovorin, and oxaliplatin. The median patient age was 63 years and 70.5% were male.

Treatment:
Patients were treated with the chemotherapy agents pemetrexed and irinotecan.

Toxicities:
The most severe reported toxicities were of grade 4 and included leucopenia and neutropenia. Grade 3 fatigue and diarrhea were also reported.

Results:
The median overall survival was 13.9 months.

Support:
One of the authors is employed by Eli Lilly.

Correspondence: Dr. C. Louvet; email: christophe.louvet@sat.ap-hop-paris.fr

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