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Melanoma treatment details. Chemotherapy. Immunotherapy. University of Chicago, Chicago, IL, United States



Survival: 5.4 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
Immunotherapy
   
Drugs:
Country: United States
   
City/State/Province: Chicago, IL
   
Hospital: University of Chicago
   
Journal: Link
   
Date: 2/2010

Description:
Patients:
This study involved 19 patients with previously treated advanced melanoma. The median patient age was 63 years and 63% were male.

Treatment:
Patients were treated with the chemotherapy agents oxaliplatin and docetaxel, and the immune therapy agent GM-CSF, which strengthens the immune system.

Toxicities:
The most severe toxicities were of grade 4. Grade 3-4 adverse events included neutropenia and fatigue.

Results:
The median overall survival was 5.4 months.

Support:
This study was supported by the pharmaceutical companies Sanofi and Berlex.

Correspondence: Dr. Thomas F. Gajewski; email: tgajewsk@medicine.bsd.uchicago.edu

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