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Prostate Cancer treatment details. Chemotherapy. Hormone. Osaka University, Suita, Japan



Survival: 23.0 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
Hormone
   
Drugs:
Country: Japan
   
City/State/Province: Suita
   
Hospital: Osaka University
   
Journal: Link
   
Date: 6/2012

Description:
Patients:
This study involved 72 men with metastatic castration-resistant prostate cancer. The median patient age was 72 years.

Treatment:
Patients were treated with the chemotherapy agents docetaxel and estramustine, as well as the steroid dexamethasone, which works as an anti-inflammatory.

Toxicities:
There were two treatment-related deaths from pneumonia. Grade 3-4 anemia, swelling, and pleural effusion (increase in fluid surrounding the lungs).

Results:
The median progression-free survival and overall survival were 6 and 23 months, respectively.

Correspondence: Dr. Kazuo Nishimura; e-mail: nisimura-ka2@mc.pref.osaka.jp

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