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Melanoma treatment details. Chemotherapy. Immunotherapy. University of California Irvine Medical Center, Orange, CA, United States



Survival: 11.4 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
Immunotherapy
   
Drugs:
Country: United States
   
City/State/Province: Orange, CA
   
Hospital: University of California Irvine Medical Center
   
Journal: Link
   
Date: 10/2011

Description:
Patients:
This phase 2 study involved 52 metastatic melanoma patients with a median age of 62 years; 71.1% were male.

Treatment:
Patients were treated with the chemotherapy agents docetaxel and vinorelbine, as well as the immune therapy agent GM-CSF, which acts to strengthen the immune system during chemotherapy.

Toxicities:
The most severe toxicities were of grade 4. Grade 3 to 4 adverse events included anemia, neutropenia, and fatigue.

Results:
The median overall survival was 11.4 months.

Correspondence: Dr. John P. Fruehauf; email: jfruehau@uci.edu

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