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Melanoma treatment details. Biologic therapy. Yale University School of Medicine, New Haven, Connecticut, United States



Survival: 12.7 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: New Haven, Connecticut
   
Hospital: Yale University School of Medicine
   
Journal: Link
   
Date: 5/2011

Description:
Patients:
This study involved 39 melanoma patients who had not previously received chemotherapy. The average patient age was 64 years and 67% were male.

Treatment:
Patients were treated with the biologic therapy agent called dasatinib, which is an inhibitor of src kinases and causes reduced melanoma cell growth.

Toxicities:
The most severe toxicities were of grade 4 and included shortness of breath and pleural effusion (fluid in the lungs). Grade 3 fatigue was also reported.

Results:
The median overall survival was 12.7 months.

Correspondence: Dr. Harriet M. Kluger; email: harriet.kluger@yale.edu

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