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Melanoma treatment details. Biologic therapy. Yale University School of Medicine, New Haven, Connecticut, United States

Survival: 12.7 months
Toxicity Grade: 4
Treatments: Biologic therapy
Country: United States
City/State/Province: New Haven, Connecticut
Hospital: Yale University School of Medicine
Journal: Link
Date: 5/2011

This study involved 39 melanoma patients who had not previously received chemotherapy. The average patient age was 64 years and 67% were male.

Patients were treated with the biologic therapy agent called dasatinib, which is an inhibitor of src kinases and causes reduced melanoma cell growth.

The most severe toxicities were of grade 4 and included shortness of breath and pleural effusion (fluid in the lungs). Grade 3 fatigue was also reported.

The median overall survival was 12.7 months.

Correspondence: Dr. Harriet M. Kluger; email:

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