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Mesothelioma Cancer treatment details. Biologic therapy. University of California, San Francisco, CA, United States

Survival: 9.7 months
Toxicity Grade: 4
Treatments: Biologic therapy
Country: United States
City/State/Province: San Francisco, CA
Hospital: University of California
Journal: Link
Date: 10/2010

This phase II study involved 51 malignant mesothelioma patients, 70% of whom were male. The median patient age was 69 years.

Patients were treated with the biologic therapy agent sorafenib, which inhibits the receptor for the VEGF protein and subsequently inhibits blood supply to the tumor.

The most severe toxicity was grade 4 fatigue. Grade 3 rash and shortness of breath were also reported.

The median overall survival was 9.7 months.

Correspondence: Dr. Pasi A. Janne; email:

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