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Brain Cancer treatment details. Alternative. University of Lausanne, Lausanne, Switzerland



Survival: 6.6 months
   
Toxicity Grade: 4
   
Treatments: Alternative
   
Drugs:
Country: Switzerland
   
City/State/Province: Lausanne
   
Hospital: University of Lausanne
   
Journal: Link
   
Date: 9/2012

Description:
Patients:
This phase 3 study involved 120 previously treated patients with recurrent glioblastoma. The median patient age was 54 years and 77% were male.

Treatment:
Patients were treated with an alternative therapy called NovoTTF-100A, which is a portable device that emits low intensity electric fields (tumor treatment fields) to physically interfere with the growth of cancer cells.

Toxicities:
The most severe adverse effects were of grade 4 and included grade 3-4 nervous system disorders. Grade 1-2 contact dermatitis (skin irritation) was also reported.

Results:
The median overall survival was 6.6 months.

Support:
Some of the authors are employed by or receive funding from Novocure (makers of NovoTTF-100A) and other pharmaceutical companies.

Correspondence: Dr. Roger Stupp; email: Roger.Stupp@chuv.ch

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