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Ovarian Cancer treatment details. Biologic therapy. Chemotherapy. University of Vermont Cancer Center, Burlington, VT, United States



Survival: 33.2 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Burlington, VT
   
Hospital: University of Vermont Cancer Center
   
Journal: Link
   
Date: 7/2012

Description:
Patients:
This phase 2 study involved 46 previously treated patients with resistant or refractory ovarian cancer. The median patient age was 64 years.

Treatment:
Patients were treated with the chemotherapy agent called pegylated liposomal doxorubicin and the biologic therapy agent bevacizumab.

Toxicities:
The most severe toxicities were grade 4 headache and neurologic complications. Grade 3 hand-foot skin reaction and increased blood pressure were also reported.

Results:
The median overall survival was 33.2 months.

Support:
This study was supported by the pharmaceutical company Genentech.

Correspondence: Dr. C. F. Verschraegen; email: claire.verschraegen@vtmednet.org

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