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Bladder Cancer treatment details. Biologic therapy. Lukas Hospital, Neuss, Germany



Survival: 3.5 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: Germany
   
City/State/Province: Neuss
   
Hospital: Lukas Hospital
   
Journal: Link
   
Date: 12/2012

Description:
Patients:
This phase 2 study involved 15 metastatic urothelial carcinoma patients who had been previously treated with platinum-based chemotherapy. The median patient age was 64.7 years and 71% were male.

Treatment:
Patients were treated with temsirolimus, a biologic therapy agent that inhibits the mTOR protein to cause cancer cell death.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 fatigue, thrombocytopenia, and neutropenia.

Results:
The median overall survival was 3.5 months.

Correspondence: Dr. Holger Gerullis ; email: holger.gerullis@gmx.net

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