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Bladder Cancer treatment details. Chemotherapy. Mansoura University, Mansoura, Egypt



Survival: 12.5 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: Egypt
   
City/State/Province: Mansoura
   
Hospital: Mansoura University
   
Journal: Link
   
Date: 8/2012

Description:
Patients:
This phase 2 study involved 40 patients with metastatic transitional cell carcinoma of the bladder who had previously received cisplatin-gemcitabine chemotherapy. The median patient age was 62 years and 80% were male.

Treatment:
Patients were treated with the chemotherapy agents methotrexate, paclitaxel, epirubicin, and carboplatin.

Toxicities:
The most severe toxicities were grade4 neuropathy (nerve disorders). Grade 3 neutropenia was reported in 30% of the patients.

Results:
The median progression-free survival was 12 months and the median overall survival was 12.5 months.

Correspondence: Dr. Amal Halim; email: amalsalahm@yahoo.com

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