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Breast Cancer treatment details. Biologic therapy. Mayo Clinic, Jacksonville, FL, United States



Survival: 12.7 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Jacksonville, FL
   
Hospital: Mayo Clinic
   
Journal: Link
   
Date: 12/2012

Description:
Patients:
This phase 2 study involved 21 female previously treated metastatic breast cancer patients. The median patient age was 58 years.

Treatment:
Patients were treated with the biologic therapy agent aflibercept, a VEGF inhibitor that interferes with tumor blood supply.

Toxicities:
The most severe toxicities were of grade 4 and included high blood pressure, shortness of breath, and heart complications.

Results:
The median overall survival was 12.7 months.

Correspondence: Dr. Edith A. Perez; email: perez.edith@mayo.edu

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