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Liver Cancer treatment details. Biologic therapy. Chinese University of Hong Kong, Hong Kong, China

Survival: 6.6 months
Toxicity Grade: 5
Treatments: Biologic therapy
Country: China
City/State/Province: Hong Kong
Hospital: Chinese University of Hong Kong
Journal: Link
Date: 9/2012

This phase 2 study involved 42 hepatocellular carcinoma patients. The median patient age was 57.5 years and 90% were male.

Patients were treated with the biologic therapy agent belinostat, which is an inhibitor of a protein involved in DNA replication and cancer cell growth.

There was one reported death due to unknown causes reported for this study. Grade 4 anemia and abdominal pain, and grade 3 vomiting were also reported.

The median overall survival was 6.6 months.

This study was supported by TopoTarget, makers of belinostat.

Correspondence: Dr. Winnie Yeo; email:

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