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Liver Cancer treatment details. Biologic therapy. Chinese University of Hong Kong, Hong Kong, China



Survival: 6.6 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: China
   
City/State/Province: Hong Kong
   
Hospital: Chinese University of Hong Kong
   
Journal: Link
   
Date: 9/2012

Description:
Patients:
This phase 2 study involved 42 hepatocellular carcinoma patients. The median patient age was 57.5 years and 90% were male.

Treatment:
Patients were treated with the biologic therapy agent belinostat, which is an inhibitor of a protein involved in DNA replication and cancer cell growth.

Toxicities:
There was one reported death due to unknown causes reported for this study. Grade 4 anemia and abdominal pain, and grade 3 vomiting were also reported.

Results:
The median overall survival was 6.6 months.

Support:
This study was supported by TopoTarget, makers of belinostat.

Correspondence: Dr. Winnie Yeo; email: winnieyeo@cuhk.edu.hk

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