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Lung Cancer treatment details. Biologic therapy. National Cancer Center, Goyang, Korea



Survival: 8.5 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: Korea
   
City/State/Province: Goyang
   
Hospital: National Cancer Center
   
Journal: Link
   
Date: 4/2012

Description:
Patients:
This phase 3 study involved 617 previously treated advanced non-small-cell lung cancer patients.. The median patient age was 60 years and 47% were male.

Treatment:
Patients were treated with the biologic therapy agent vandetanib, which is a VEGF inhibitor that interferes with tumor blood supply.

Toxicities:
Treatment-related deaths were reported, with causes including respiratory problems. Grade 3 or higher diarrhea, rash, and high blood pressure were also reported.

Results:
The median overall survival was 8.5 months.

Support:
This study was supported by the pharmaceutical company AstraZeneca.

Correspondence: Dr. Jin Soo Lee; email: jslee@ncc.re.kr

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