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Rectal Cancer treatment details. Chemotherapy. Radiation. Surgery. Lyon Sud Pierre Benite, Lyon, France

Survival: ?
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Eloxatin
Country: France
City/State/Province: Lyon
Hospital: Lyon Sud Pierre Benite
Journal: Link
Date: 3/2003

Patients: Forty patients with locally advanced rectal cancer were involved in this Phase II study.

Treatment: Treatment consisted of the combination of radiation, fluorouracil (adrucil), and oxaliplatin (eloxatin) followed by surgery.

Toxicity: Grade 3 to 4 toxicity was seen in seven patients (17%) for a total of 16 different toxicities. These toxicities included: hematologic, liver function, neurotoxicity, gastrointestinal toxicity, hand-foot syndrome, fever, and fatigue.

Results: An objective clinical response was seen in 75% of patients. Overall median survival was not discussed.

Correspondence: Jean-Pierre Gerard, MD

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