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Prostate Cancer treatment details. Biologic therapy. Chemotherapy. Kantonsspital Graub€unden, Chur, Switzerland



Survival: 13.3 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Switzerland
   
City/State/Province: Chur
   
Hospital: Kantonsspital Graub€unden
   
Journal: Link
   
Date: 11/2012

Description:
Patients:
This phase 2 study involved previously treated metastatic castration-resistant prostate cancer patients with a median age of 68 years.

Treatment:
Patients were treated with the chemotherapy agent docetaxel and the biologic therapy agent cetuximab (a monoclonal antibody against EGFR that interferes with tumor cell growth).

Toxicities:
There were two treatment-related deaths due to infection. Grade 4 allergic reaction and pain, and grade 3 fatigue and skin toxicity were also reported.

Results:
The median overall survival was 13.3 months.

Support:
This study was supported by Merck and Sanofi Aventis.

Correspondence: Dr. Richard Cathomas; email: richard.cathomas@ksgr.ch

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