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Brain Cancer treatment details. Biologic therapy. Cleveland Clinic, Cleveland, OH, United States



Survival: 5.7 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Cleveland, OH
   
Hospital: Cleveland Clinic
   
Journal: Link
   
Date: 4/2013

Description:
Patients:
This phase 2 study involved 56 recurrent or progressive glioblastoma patients. The median patient age was 56 years and 63% were male.

Treatment:
Patients were treated with the biologic therapy agents erlotinib and sorafenib, which are kinase inhibitors that interfere with tumor growth.

Toxicities:
The most severe toxicities were grade 3-4 fatigue and pancreatic problems.

Results:
The median overall survival was 5.7 months.

Correspondence: Dr. David M. Peereboom; email: peerebd@ccf.org

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