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Brain Cancer treatment details. Chemotherapy. Radiation. Harvard Medical School, Boston, MA, United States



Survival: 13.0 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
Radiation
   
Drugs:
Country: United States
   
City/State/Province: Boston, MA
   
Hospital: Harvard Medical School
   
Journal: Link
   
Date: 10/2012

Description:
Patients:
This phase 2 study involved 20 elderly (over 65) glioblastoma patients. The median patient age was 75.4 years and 9 were male.

Treatment:
Patients were treated with radiation therapy and the chemotherapy agent temozolomide.

Toxicities:
Treatment-related deaths due to sepsis (infection) and pulmonary embolism were reported. Grade 2 cerebral swelling was also reported.

Results:
The median overall survival was 13 months and the median progression-free survival was 11 months.

Correspondence: Dr. Anand Mahadevan; email: amahadev@bidmc.harvard.edu

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